Introduction: Psoriasis is a chronic inflammatory skin disease depicted by deforming, inconsistent penetrations, and repeated proliferative and inflammatory skin ailment.Local treatment with topical agents is one of the substantial modalities in the remediation of this ailment.Efforts are directed toward the development of novel efficacious topical
A novel risk model construction and immune landscape analysis of gastric cancer based on cuproptosis-related long noncoding RNAs
Recent studies have identified cuproptosis, a new mechanism of regulating cell death.Accumulating evidence suggests that copper homeostasis is associated with tumorigenesis and tumor progression, however, the clinical significance of cuproptosis in gastric cancer (GC) is unclear.In this study, we obtained 26 prognostic cuproptosis-related lncRNAs (
The mind body problem, part three: ascension of sexual function to cerebral level
Physiologically, the somatic nervous system intervenes in external interaction between the body and environment, while autonomic nervous system ensures the functioning of internal organs.We present in this paper a psycho-physiological perspective suggesting that mental function (somatic in nature, because coordinates environmental interaction) is c
Administration of BNT162b2 mRNA COVID-19 vaccine to subjects with various allergic backgrounds
BackgroundThe mRNA-based COVID-19 vaccine was introduced to the general public in December 2020.Shortly thereafter, safety concerns were raised due to the reporting of allergic reactions.Allergy-related disorders were suspected to be significant risk factors and the excipient polyethylene glycol was suggested to be a robust allergen.MethodsThis is
Key Problems to Be Solved Possibly Using Machine Learning in Heavy Ion Collisions
Heavy-ion collisions provide a unique opportunity to study the nuclear equation of state for a wide range of densities, temperatures, and neutron-proton asymmetries in the laboratory.Transport models are the main method to obtain physics information on the nuclear equation of state and in-medium properties of particles from low to relativistic-ener